Contrast Enhanced Spectral Mammography - a UK centre experience
Association of Breast Surgery ePoster Library. Ginawi A. 05/15/17; 166185; P030
Alaaeldin Ginawi
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Abstract
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Introduction
Contrast enhanced spectral mammography (CESM) is a breast imaging technique combining standard mammogram and the utilisation of intravenous injection of contrast media for better visualisation of lesions. We aim to assess the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of CESM. Also, compare CESM and breast MRI to histological size in a subgroup of patients.
Methods
Retrospective analysis of prospectively collected data was performed. CESM was performed in 128 consecutive patients who presented with clinically malignant breast lump (P4/5). CESM and MRI were performed in a subgroup of 29 patients where MRI was indicated by NICE guidelines to allow comparison between both modalities and histological size.
Results
134 CESMs were performed in 128 patients. The sensitivity, specificity, PPV and NPV of CESM were 98.1%, 66.6%, 98.1% and 66.6 % respectively. 29 patients had CESM, MRI and surgery. Comparing CESM to MRI, both were sensitive in 28 patients (96 %), One false negative result for both. The average dimension of the largest lesion measured in CESM was 28.91 mm (SD 22.94), 29.51 mm (SD 22.71) in MRI versus 32.37 mm (SD 22.47) in the final histology.
Conclusion
CESM has comparable sensitivity and accuracy to MRI. With added advantages of simple implementation of CESM within one stop clinic, patients' comfort, shallow learning curve for radiologists and surgeons' friendly images. CESM appear to be a promising modality which could be used in the future on a wider scale.
Contrast enhanced spectral mammography (CESM) is a breast imaging technique combining standard mammogram and the utilisation of intravenous injection of contrast media for better visualisation of lesions. We aim to assess the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of CESM. Also, compare CESM and breast MRI to histological size in a subgroup of patients.
Methods
Retrospective analysis of prospectively collected data was performed. CESM was performed in 128 consecutive patients who presented with clinically malignant breast lump (P4/5). CESM and MRI were performed in a subgroup of 29 patients where MRI was indicated by NICE guidelines to allow comparison between both modalities and histological size.
Results
134 CESMs were performed in 128 patients. The sensitivity, specificity, PPV and NPV of CESM were 98.1%, 66.6%, 98.1% and 66.6 % respectively. 29 patients had CESM, MRI and surgery. Comparing CESM to MRI, both were sensitive in 28 patients (96 %), One false negative result for both. The average dimension of the largest lesion measured in CESM was 28.91 mm (SD 22.94), 29.51 mm (SD 22.71) in MRI versus 32.37 mm (SD 22.47) in the final histology.
Conclusion
CESM has comparable sensitivity and accuracy to MRI. With added advantages of simple implementation of CESM within one stop clinic, patients' comfort, shallow learning curve for radiologists and surgeons' friendly images. CESM appear to be a promising modality which could be used in the future on a wider scale.
Introduction
Contrast enhanced spectral mammography (CESM) is a breast imaging technique combining standard mammogram and the utilisation of intravenous injection of contrast media for better visualisation of lesions. We aim to assess the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of CESM. Also, compare CESM and breast MRI to histological size in a subgroup of patients.
Methods
Retrospective analysis of prospectively collected data was performed. CESM was performed in 128 consecutive patients who presented with clinically malignant breast lump (P4/5). CESM and MRI were performed in a subgroup of 29 patients where MRI was indicated by NICE guidelines to allow comparison between both modalities and histological size.
Results
134 CESMs were performed in 128 patients. The sensitivity, specificity, PPV and NPV of CESM were 98.1%, 66.6%, 98.1% and 66.6 % respectively. 29 patients had CESM, MRI and surgery. Comparing CESM to MRI, both were sensitive in 28 patients (96 %), One false negative result for both. The average dimension of the largest lesion measured in CESM was 28.91 mm (SD 22.94), 29.51 mm (SD 22.71) in MRI versus 32.37 mm (SD 22.47) in the final histology.
Conclusion
CESM has comparable sensitivity and accuracy to MRI. With added advantages of simple implementation of CESM within one stop clinic, patients' comfort, shallow learning curve for radiologists and surgeons' friendly images. CESM appear to be a promising modality which could be used in the future on a wider scale.
Contrast enhanced spectral mammography (CESM) is a breast imaging technique combining standard mammogram and the utilisation of intravenous injection of contrast media for better visualisation of lesions. We aim to assess the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of CESM. Also, compare CESM and breast MRI to histological size in a subgroup of patients.
Methods
Retrospective analysis of prospectively collected data was performed. CESM was performed in 128 consecutive patients who presented with clinically malignant breast lump (P4/5). CESM and MRI were performed in a subgroup of 29 patients where MRI was indicated by NICE guidelines to allow comparison between both modalities and histological size.
Results
134 CESMs were performed in 128 patients. The sensitivity, specificity, PPV and NPV of CESM were 98.1%, 66.6%, 98.1% and 66.6 % respectively. 29 patients had CESM, MRI and surgery. Comparing CESM to MRI, both were sensitive in 28 patients (96 %), One false negative result for both. The average dimension of the largest lesion measured in CESM was 28.91 mm (SD 22.94), 29.51 mm (SD 22.71) in MRI versus 32.37 mm (SD 22.47) in the final histology.
Conclusion
CESM has comparable sensitivity and accuracy to MRI. With added advantages of simple implementation of CESM within one stop clinic, patients' comfort, shallow learning curve for radiologists and surgeons' friendly images. CESM appear to be a promising modality which could be used in the future on a wider scale.
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