Comparison of 2 radioisotope injection techniques for sentinal lymph node biopsy in Breast Cancer
Association of Breast Surgery ePoster Library. Hughes M. 05/15/17; 166280; P168
Michael Hughes
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Abstract
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Aim: To compare peri-areolar and peri tumoural injection techniques in sentinal lymph node biopsy for breast cancer
Methods: All patients undergoing SLNB in the Belfast City hospital from 24/5/16 - 5/7/16 were eligible for inclusion. Patients were excluded if they had received isotope injection not on the day of surgery or if data collection was not complete. Intraoperative radioactivity counts were recorded using a GammaFinder® probe at; site of injection, axilla pre operatively, node post removal. Counts were analyzed for each technique. Histological samples were reviewed for each technique and the number of nodes, including positive nodes were also compared. A students t-test was performed on the data.
Results: Twenty two patients in total were eligible for data collection. The peri-areolar technique had statistically significant ,p value = less than 0.05 ,higher reading for axilla counts (166 Vs 7.4) and nodal counts (1140 Vs 115). There was no difference between number of nodes removed (2.3 Vs 3.6) or the histological diagnosis of the nodes.
Discussion: Peri-areolar injection technique compared to the Peri Tumoural results in significantly higher mean nodal count scores. This results in easier and more reliable detection of sentinel nodes. This however does not reflect in the number of nodes removed.
Methods: All patients undergoing SLNB in the Belfast City hospital from 24/5/16 - 5/7/16 were eligible for inclusion. Patients were excluded if they had received isotope injection not on the day of surgery or if data collection was not complete. Intraoperative radioactivity counts were recorded using a GammaFinder® probe at; site of injection, axilla pre operatively, node post removal. Counts were analyzed for each technique. Histological samples were reviewed for each technique and the number of nodes, including positive nodes were also compared. A students t-test was performed on the data.
Results: Twenty two patients in total were eligible for data collection. The peri-areolar technique had statistically significant ,p value = less than 0.05 ,higher reading for axilla counts (166 Vs 7.4) and nodal counts (1140 Vs 115). There was no difference between number of nodes removed (2.3 Vs 3.6) or the histological diagnosis of the nodes.
Discussion: Peri-areolar injection technique compared to the Peri Tumoural results in significantly higher mean nodal count scores. This results in easier and more reliable detection of sentinel nodes. This however does not reflect in the number of nodes removed.
Aim: To compare peri-areolar and peri tumoural injection techniques in sentinal lymph node biopsy for breast cancer
Methods: All patients undergoing SLNB in the Belfast City hospital from 24/5/16 - 5/7/16 were eligible for inclusion. Patients were excluded if they had received isotope injection not on the day of surgery or if data collection was not complete. Intraoperative radioactivity counts were recorded using a GammaFinder® probe at; site of injection, axilla pre operatively, node post removal. Counts were analyzed for each technique. Histological samples were reviewed for each technique and the number of nodes, including positive nodes were also compared. A students t-test was performed on the data.
Results: Twenty two patients in total were eligible for data collection. The peri-areolar technique had statistically significant ,p value = less than 0.05 ,higher reading for axilla counts (166 Vs 7.4) and nodal counts (1140 Vs 115). There was no difference between number of nodes removed (2.3 Vs 3.6) or the histological diagnosis of the nodes.
Discussion: Peri-areolar injection technique compared to the Peri Tumoural results in significantly higher mean nodal count scores. This results in easier and more reliable detection of sentinel nodes. This however does not reflect in the number of nodes removed.
Methods: All patients undergoing SLNB in the Belfast City hospital from 24/5/16 - 5/7/16 were eligible for inclusion. Patients were excluded if they had received isotope injection not on the day of surgery or if data collection was not complete. Intraoperative radioactivity counts were recorded using a GammaFinder® probe at; site of injection, axilla pre operatively, node post removal. Counts were analyzed for each technique. Histological samples were reviewed for each technique and the number of nodes, including positive nodes were also compared. A students t-test was performed on the data.
Results: Twenty two patients in total were eligible for data collection. The peri-areolar technique had statistically significant ,p value = less than 0.05 ,higher reading for axilla counts (166 Vs 7.4) and nodal counts (1140 Vs 115). There was no difference between number of nodes removed (2.3 Vs 3.6) or the histological diagnosis of the nodes.
Discussion: Peri-areolar injection technique compared to the Peri Tumoural results in significantly higher mean nodal count scores. This results in easier and more reliable detection of sentinel nodes. This however does not reflect in the number of nodes removed.
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