Impact of Neoadjuvant Chemotherapy on Axillary Tumour Burden
Association of Breast Surgery ePoster Library. Kiritharamohan P. 05/13/19; 257062; P018
Paran Kiritharamohan
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P018
Topic: Axilla
Aim: Neoadjuvant chemotherapy (NAC) usually results in partial / complete eradication of cancer in the breast. We studied the impact of NAC on the axillary tumour burden in early breast cancer patients with node-positive axilla.M & M: We studied the axillary outcome of patients diagnosed with node-positive axilla at the time of diagnosis by US-guided FNAC , and compared this between those who received NAC and those who had surgery first. Results: 103 female patients were identified, 97 were suitable. One patient had bilateral node positive cancers. All had axillary clearance except 4 who had sentinel lymph node biopsy (SLNB). The baseline & outcome data presented in Table;Neoadjuvant Chemotherapy (n=48)Surgery (n=49)Median age (range)54 (33-77)65 (31-88)Median primary tumour size on Ultrasound (mm) (range)26 (7-50)22.5 (0*-47)Core biopsy histology Invasive Ductal4447 Invasive Lobular42Type of Surgery Mastectomy2530 Breast Conservation2319Median no of nodes with macrometastases (range)1 (0-29)3 (0-59)Median percentage of nodes with macrometastases (Number involved / Number removed) (range)5 (0-95)20 (0-100)
Topic: Axilla
Aim: Neoadjuvant chemotherapy (NAC) usually results in partial / complete eradication of cancer in the breast. We studied the impact of NAC on the axillary tumour burden in early breast cancer patients with node-positive axilla.M & M: We studied the axillary outcome of patients diagnosed with node-positive axilla at the time of diagnosis by US-guided FNAC , and compared this between those who received NAC and those who had surgery first. Results: 103 female patients were identified, 97 were suitable. One patient had bilateral node positive cancers. All had axillary clearance except 4 who had sentinel lymph node biopsy (SLNB). The baseline & outcome data presented in Table;Neoadjuvant Chemotherapy (n=48)Surgery (n=49)Median age (range)54 (33-77)65 (31-88)Median primary tumour size on Ultrasound (mm) (range)26 (7-50)22.5 (0*-47)Core biopsy histology Invasive Ductal4447 Invasive Lobular42Type of Surgery Mastectomy2530 Breast Conservation2319Median no of nodes with macrometastases (range)1 (0-29)3 (0-59)Median percentage of nodes with macrometastases (Number involved / Number removed) (range)5 (0-95)20 (0-100)
P018
Topic: Axilla
Aim: Neoadjuvant chemotherapy (NAC) usually results in partial / complete eradication of cancer in the breast. We studied the impact of NAC on the axillary tumour burden in early breast cancer patients with node-positive axilla.M & M: We studied the axillary outcome of patients diagnosed with node-positive axilla at the time of diagnosis by US-guided FNAC , and compared this between those who received NAC and those who had surgery first. Results: 103 female patients were identified, 97 were suitable. One patient had bilateral node positive cancers. All had axillary clearance except 4 who had sentinel lymph node biopsy (SLNB). The baseline & outcome data presented in Table;Neoadjuvant Chemotherapy (n=48)Surgery (n=49)Median age (range)54 (33-77)65 (31-88)Median primary tumour size on Ultrasound (mm) (range)26 (7-50)22.5 (0*-47)Core biopsy histology Invasive Ductal4447 Invasive Lobular42Type of Surgery Mastectomy2530 Breast Conservation2319Median no of nodes with macrometastases (range)1 (0-29)3 (0-59)Median percentage of nodes with macrometastases (Number involved / Number removed) (range)5 (0-95)20 (0-100)
Topic: Axilla
Aim: Neoadjuvant chemotherapy (NAC) usually results in partial / complete eradication of cancer in the breast. We studied the impact of NAC on the axillary tumour burden in early breast cancer patients with node-positive axilla.M & M: We studied the axillary outcome of patients diagnosed with node-positive axilla at the time of diagnosis by US-guided FNAC , and compared this between those who received NAC and those who had surgery first. Results: 103 female patients were identified, 97 were suitable. One patient had bilateral node positive cancers. All had axillary clearance except 4 who had sentinel lymph node biopsy (SLNB). The baseline & outcome data presented in Table;Neoadjuvant Chemotherapy (n=48)Surgery (n=49)Median age (range)54 (33-77)65 (31-88)Median primary tumour size on Ultrasound (mm) (range)26 (7-50)22.5 (0*-47)Core biopsy histology Invasive Ductal4447 Invasive Lobular42Type of Surgery Mastectomy2530 Breast Conservation2319Median no of nodes with macrometastases (range)1 (0-29)3 (0-59)Median percentage of nodes with macrometastases (Number involved / Number removed) (range)5 (0-95)20 (0-100)
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