Assessment of Rates of Local Recurrence in a Symptomatic Centre Following Breast Cancer Surgery
Association of Breast Surgery ePoster Library. Michael S. 05/13/19; 257090; P046
Sarah Michael
REGULAR CONTENT
Login now to access Regular content available to all registered users.
Abstract
Discussion Forum (0)
Rate & Comment (0)
P046
Topic: Breast surgery
Introduction: The Association of Breast Surgery (ABS) recommends mandatory rates for local recurrence of 5% at 5 years following breast cancer surgery, with <3% being the optimal. This study evaluates the rates of local and distant recurrence at one symptomatic centre. Methods : Data including patient demographics, tumour characteristics and surgical treatment from all patients undergoing breast surgery between 2011 and 2012 was collected from MDT, electronic patient records; operation notes and pathology reports. The endpoints in this study were local and distant recurrence; and disease-free survival. Results:There was 3.4% local and 8.5% distant recurrences. The median time to local and distant recurrence was 33.7 months (9.4-88.0) and 35.4 months (5.7-76.9) respectively. Nodal stage predicted local recurrence, with an OR for stage N3 of 8.353 (p=0.023) and also predicted distant recurrence in stage N3 with an OR of 17.085 (p=<0.0001). Mastectomy was associated with a worse outcome compared to wide local excisions for distant recurrence (OR 2.456, p=0.037).AllWLEMastectomyP-valuen506257255Mean Tumour Size (mm)25.318.831.7Node negative330 (65.2%)198 (78.9%)132 (51.8%)<0.001N2/N363 (12.4%)16 (6.4%)47 (18.5%)<0.001RecurrencesLocal17 (3.4%)6 (2.4%)11 (4.3%)Distant43 (8.5%)10 (4.0%)32 (13.0%)<0.001Conclusion: The ABS mandatory target for local recurrence was met by this centre. Distant and local recurrences were more likely to occur after 3 years and nodal status predicted both with high fidelity. Furthermore, mastectomy was associated with higher rates of distant recurrence.
Topic: Breast surgery
Introduction: The Association of Breast Surgery (ABS) recommends mandatory rates for local recurrence of 5% at 5 years following breast cancer surgery, with <3% being the optimal. This study evaluates the rates of local and distant recurrence at one symptomatic centre. Methods : Data including patient demographics, tumour characteristics and surgical treatment from all patients undergoing breast surgery between 2011 and 2012 was collected from MDT, electronic patient records; operation notes and pathology reports. The endpoints in this study were local and distant recurrence; and disease-free survival. Results:There was 3.4% local and 8.5% distant recurrences. The median time to local and distant recurrence was 33.7 months (9.4-88.0) and 35.4 months (5.7-76.9) respectively. Nodal stage predicted local recurrence, with an OR for stage N3 of 8.353 (p=0.023) and also predicted distant recurrence in stage N3 with an OR of 17.085 (p=<0.0001). Mastectomy was associated with a worse outcome compared to wide local excisions for distant recurrence (OR 2.456, p=0.037).AllWLEMastectomyP-valuen506257255Mean Tumour Size (mm)25.318.831.7Node negative330 (65.2%)198 (78.9%)132 (51.8%)<0.001N2/N363 (12.4%)16 (6.4%)47 (18.5%)<0.001RecurrencesLocal17 (3.4%)6 (2.4%)11 (4.3%)Distant43 (8.5%)10 (4.0%)32 (13.0%)<0.001Conclusion: The ABS mandatory target for local recurrence was met by this centre. Distant and local recurrences were more likely to occur after 3 years and nodal status predicted both with high fidelity. Furthermore, mastectomy was associated with higher rates of distant recurrence.
P046
Topic: Breast surgery
Introduction: The Association of Breast Surgery (ABS) recommends mandatory rates for local recurrence of 5% at 5 years following breast cancer surgery, with <3% being the optimal. This study evaluates the rates of local and distant recurrence at one symptomatic centre. Methods : Data including patient demographics, tumour characteristics and surgical treatment from all patients undergoing breast surgery between 2011 and 2012 was collected from MDT, electronic patient records; operation notes and pathology reports. The endpoints in this study were local and distant recurrence; and disease-free survival. Results:There was 3.4% local and 8.5% distant recurrences. The median time to local and distant recurrence was 33.7 months (9.4-88.0) and 35.4 months (5.7-76.9) respectively. Nodal stage predicted local recurrence, with an OR for stage N3 of 8.353 (p=0.023) and also predicted distant recurrence in stage N3 with an OR of 17.085 (p=<0.0001). Mastectomy was associated with a worse outcome compared to wide local excisions for distant recurrence (OR 2.456, p=0.037).AllWLEMastectomyP-valuen506257255Mean Tumour Size (mm)25.318.831.7Node negative330 (65.2%)198 (78.9%)132 (51.8%)<0.001N2/N363 (12.4%)16 (6.4%)47 (18.5%)<0.001RecurrencesLocal17 (3.4%)6 (2.4%)11 (4.3%)Distant43 (8.5%)10 (4.0%)32 (13.0%)<0.001Conclusion: The ABS mandatory target for local recurrence was met by this centre. Distant and local recurrences were more likely to occur after 3 years and nodal status predicted both with high fidelity. Furthermore, mastectomy was associated with higher rates of distant recurrence.
Topic: Breast surgery
Introduction: The Association of Breast Surgery (ABS) recommends mandatory rates for local recurrence of 5% at 5 years following breast cancer surgery, with <3% being the optimal. This study evaluates the rates of local and distant recurrence at one symptomatic centre. Methods : Data including patient demographics, tumour characteristics and surgical treatment from all patients undergoing breast surgery between 2011 and 2012 was collected from MDT, electronic patient records; operation notes and pathology reports. The endpoints in this study were local and distant recurrence; and disease-free survival. Results:There was 3.4% local and 8.5% distant recurrences. The median time to local and distant recurrence was 33.7 months (9.4-88.0) and 35.4 months (5.7-76.9) respectively. Nodal stage predicted local recurrence, with an OR for stage N3 of 8.353 (p=0.023) and also predicted distant recurrence in stage N3 with an OR of 17.085 (p=<0.0001). Mastectomy was associated with a worse outcome compared to wide local excisions for distant recurrence (OR 2.456, p=0.037).AllWLEMastectomyP-valuen506257255Mean Tumour Size (mm)25.318.831.7Node negative330 (65.2%)198 (78.9%)132 (51.8%)<0.001N2/N363 (12.4%)16 (6.4%)47 (18.5%)<0.001RecurrencesLocal17 (3.4%)6 (2.4%)11 (4.3%)Distant43 (8.5%)10 (4.0%)32 (13.0%)<0.001Conclusion: The ABS mandatory target for local recurrence was met by this centre. Distant and local recurrences were more likely to occur after 3 years and nodal status predicted both with high fidelity. Furthermore, mastectomy was associated with higher rates of distant recurrence.
Code of conduct/disclaimer available in General Terms & Conditions
{{ help_message }}
{{filter}}