Does selective use of MRI in neoadjuvant setting facilitates surgical decision making?
Association of Breast Surgery ePoster Library. Yuan Khor B. 05/13/19; 257108; P064
Bo Yuan Khor
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P064
Topic: Breast surgery
Introduction The aim of this study was to investigate the role of MRI in select group of neoadjuvant chemotherapy patients and its impact on surgical decision making. Methods This is a study on 36 consecutive patients between Aug 2016-18, with histologically proven breast cancer who received neoadjuvant chemotherapy (NAC) followed by curative surgery at a single centre. Information on tumour biology, MRI measurements, breast cancer management were obtained using hospital computer database. Results Of 36 patients, majority were over 40 (69.4%), 66.7% had unifocal and 55.6% had node negative disease at presentation. Following local protocol, 17 (47.2%) patients underwent breast MRI before and after NAC to help guide decision making for breast conserving surgery. 19 (52.8%) patients did not undergo breast MRI as mastectomy was planned in MDT for reasons such as inflammatory cancer, multicentricity and patient's choice. Patients receiving NAC, who did not have MRI, were monitored with US. Of 17 patients who underwent breast MRI, 11 (64.7%) patients had complete radiological response after NAC. 9 (52.9%) patients who had breast MRI went on to have WLE while 2 had mastectomy (patient's choice). Of the 11 patients who had complete radiological response on breast MRI, 8 (72.7%) had complete pathological response on final histology. All patients who did not undergo MRI, went on to have mastectomy as decided in MDT before offering NAC. Conclusions Selective use of MRI in patients receiving neo-adjuvant chemotherapy is cost-effective, helps in closely monitoring the disease response and facilitates surgical decision making.
Topic: Breast surgery
Introduction The aim of this study was to investigate the role of MRI in select group of neoadjuvant chemotherapy patients and its impact on surgical decision making. Methods This is a study on 36 consecutive patients between Aug 2016-18, with histologically proven breast cancer who received neoadjuvant chemotherapy (NAC) followed by curative surgery at a single centre. Information on tumour biology, MRI measurements, breast cancer management were obtained using hospital computer database. Results Of 36 patients, majority were over 40 (69.4%), 66.7% had unifocal and 55.6% had node negative disease at presentation. Following local protocol, 17 (47.2%) patients underwent breast MRI before and after NAC to help guide decision making for breast conserving surgery. 19 (52.8%) patients did not undergo breast MRI as mastectomy was planned in MDT for reasons such as inflammatory cancer, multicentricity and patient's choice. Patients receiving NAC, who did not have MRI, were monitored with US. Of 17 patients who underwent breast MRI, 11 (64.7%) patients had complete radiological response after NAC. 9 (52.9%) patients who had breast MRI went on to have WLE while 2 had mastectomy (patient's choice). Of the 11 patients who had complete radiological response on breast MRI, 8 (72.7%) had complete pathological response on final histology. All patients who did not undergo MRI, went on to have mastectomy as decided in MDT before offering NAC. Conclusions Selective use of MRI in patients receiving neo-adjuvant chemotherapy is cost-effective, helps in closely monitoring the disease response and facilitates surgical decision making.
P064
Topic: Breast surgery
Introduction The aim of this study was to investigate the role of MRI in select group of neoadjuvant chemotherapy patients and its impact on surgical decision making. Methods This is a study on 36 consecutive patients between Aug 2016-18, with histologically proven breast cancer who received neoadjuvant chemotherapy (NAC) followed by curative surgery at a single centre. Information on tumour biology, MRI measurements, breast cancer management were obtained using hospital computer database. Results Of 36 patients, majority were over 40 (69.4%), 66.7% had unifocal and 55.6% had node negative disease at presentation. Following local protocol, 17 (47.2%) patients underwent breast MRI before and after NAC to help guide decision making for breast conserving surgery. 19 (52.8%) patients did not undergo breast MRI as mastectomy was planned in MDT for reasons such as inflammatory cancer, multicentricity and patient's choice. Patients receiving NAC, who did not have MRI, were monitored with US. Of 17 patients who underwent breast MRI, 11 (64.7%) patients had complete radiological response after NAC. 9 (52.9%) patients who had breast MRI went on to have WLE while 2 had mastectomy (patient's choice). Of the 11 patients who had complete radiological response on breast MRI, 8 (72.7%) had complete pathological response on final histology. All patients who did not undergo MRI, went on to have mastectomy as decided in MDT before offering NAC. Conclusions Selective use of MRI in patients receiving neo-adjuvant chemotherapy is cost-effective, helps in closely monitoring the disease response and facilitates surgical decision making.
Topic: Breast surgery
Introduction The aim of this study was to investigate the role of MRI in select group of neoadjuvant chemotherapy patients and its impact on surgical decision making. Methods This is a study on 36 consecutive patients between Aug 2016-18, with histologically proven breast cancer who received neoadjuvant chemotherapy (NAC) followed by curative surgery at a single centre. Information on tumour biology, MRI measurements, breast cancer management were obtained using hospital computer database. Results Of 36 patients, majority were over 40 (69.4%), 66.7% had unifocal and 55.6% had node negative disease at presentation. Following local protocol, 17 (47.2%) patients underwent breast MRI before and after NAC to help guide decision making for breast conserving surgery. 19 (52.8%) patients did not undergo breast MRI as mastectomy was planned in MDT for reasons such as inflammatory cancer, multicentricity and patient's choice. Patients receiving NAC, who did not have MRI, were monitored with US. Of 17 patients who underwent breast MRI, 11 (64.7%) patients had complete radiological response after NAC. 9 (52.9%) patients who had breast MRI went on to have WLE while 2 had mastectomy (patient's choice). Of the 11 patients who had complete radiological response on breast MRI, 8 (72.7%) had complete pathological response on final histology. All patients who did not undergo MRI, went on to have mastectomy as decided in MDT before offering NAC. Conclusions Selective use of MRI in patients receiving neo-adjuvant chemotherapy is cost-effective, helps in closely monitoring the disease response and facilitates surgical decision making.
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