Primary Radiotherapy And Deep inferior epigastric artery perforator (DIEP) flAp study (PRADA): Aesthetic Outcome and Patient Satisfaction at one year.
Association of Breast Surgery ePoster Library. Godden A. 05/13/19; 257152; P109
Ms. Amy Godden
REGULAR CONTENT
Login now to access Regular content available to all registered users.
Abstract
Discussion Forum (0)
Rate & Comment (0)
P109
Topic: Oncoplastic and aesthetic surgery
Introduction: Radiotherapy in the context of autologous flap reconstruction is a hot topic and no consensus has been reached. The PRADA study (NCT02771938)is a safety and feasibility study of neoadjuvant radiotherapy (NRT) prior to mastectomy and DIEP flap reconstruction. Secondary outcome measures include Patient Reported Outcome Measures (PROMs) and panel assessment of aesthetic outcome using 3D images. MethodsWomen undergoing neoadjuvant chemotherapy (NACT) who will also require radiotherapy were invited to join an observational cohort study evaluating the safety and feasibility of NACT and NRT with mastectomy and DIEP reconstruction 2-6 weeks later. 3d surface images were obtained at baseline, 3, and 12 months, alongside the validated BREAST-Q Reconstruction Module. Results11 of 17 women in the aesthetic outcome subgroup have reached 12 months follow-up. The median BREAST-Q score for ‘satisfaction with breasts' was 48/100 at baseline (n=13), 73/100 at 3 months (n=13), and 81/100 at 12 months (n=9 {6 have not reached 12 months}). Panel assessment is scheduled for March when all participants will have reached study completion. ConclusionsPatient satisfaction with reconstruction is higher for PRADA than most other series. This may be due to short follow up or patients perceiving an advantage from participation in the study. The expert panel assessment will be an important comparison. A randomised controlled trial is planned to further assess this pathway.
Topic: Oncoplastic and aesthetic surgery
Introduction: Radiotherapy in the context of autologous flap reconstruction is a hot topic and no consensus has been reached. The PRADA study (NCT02771938)is a safety and feasibility study of neoadjuvant radiotherapy (NRT) prior to mastectomy and DIEP flap reconstruction. Secondary outcome measures include Patient Reported Outcome Measures (PROMs) and panel assessment of aesthetic outcome using 3D images. MethodsWomen undergoing neoadjuvant chemotherapy (NACT) who will also require radiotherapy were invited to join an observational cohort study evaluating the safety and feasibility of NACT and NRT with mastectomy and DIEP reconstruction 2-6 weeks later. 3d surface images were obtained at baseline, 3, and 12 months, alongside the validated BREAST-Q Reconstruction Module. Results11 of 17 women in the aesthetic outcome subgroup have reached 12 months follow-up. The median BREAST-Q score for ‘satisfaction with breasts' was 48/100 at baseline (n=13), 73/100 at 3 months (n=13), and 81/100 at 12 months (n=9 {6 have not reached 12 months}). Panel assessment is scheduled for March when all participants will have reached study completion. ConclusionsPatient satisfaction with reconstruction is higher for PRADA than most other series. This may be due to short follow up or patients perceiving an advantage from participation in the study. The expert panel assessment will be an important comparison. A randomised controlled trial is planned to further assess this pathway.
P109
Topic: Oncoplastic and aesthetic surgery
Introduction: Radiotherapy in the context of autologous flap reconstruction is a hot topic and no consensus has been reached. The PRADA study (NCT02771938)is a safety and feasibility study of neoadjuvant radiotherapy (NRT) prior to mastectomy and DIEP flap reconstruction. Secondary outcome measures include Patient Reported Outcome Measures (PROMs) and panel assessment of aesthetic outcome using 3D images. MethodsWomen undergoing neoadjuvant chemotherapy (NACT) who will also require radiotherapy were invited to join an observational cohort study evaluating the safety and feasibility of NACT and NRT with mastectomy and DIEP reconstruction 2-6 weeks later. 3d surface images were obtained at baseline, 3, and 12 months, alongside the validated BREAST-Q Reconstruction Module. Results11 of 17 women in the aesthetic outcome subgroup have reached 12 months follow-up. The median BREAST-Q score for ‘satisfaction with breasts' was 48/100 at baseline (n=13), 73/100 at 3 months (n=13), and 81/100 at 12 months (n=9 {6 have not reached 12 months}). Panel assessment is scheduled for March when all participants will have reached study completion. ConclusionsPatient satisfaction with reconstruction is higher for PRADA than most other series. This may be due to short follow up or patients perceiving an advantage from participation in the study. The expert panel assessment will be an important comparison. A randomised controlled trial is planned to further assess this pathway.
Topic: Oncoplastic and aesthetic surgery
Introduction: Radiotherapy in the context of autologous flap reconstruction is a hot topic and no consensus has been reached. The PRADA study (NCT02771938)is a safety and feasibility study of neoadjuvant radiotherapy (NRT) prior to mastectomy and DIEP flap reconstruction. Secondary outcome measures include Patient Reported Outcome Measures (PROMs) and panel assessment of aesthetic outcome using 3D images. MethodsWomen undergoing neoadjuvant chemotherapy (NACT) who will also require radiotherapy were invited to join an observational cohort study evaluating the safety and feasibility of NACT and NRT with mastectomy and DIEP reconstruction 2-6 weeks later. 3d surface images were obtained at baseline, 3, and 12 months, alongside the validated BREAST-Q Reconstruction Module. Results11 of 17 women in the aesthetic outcome subgroup have reached 12 months follow-up. The median BREAST-Q score for ‘satisfaction with breasts' was 48/100 at baseline (n=13), 73/100 at 3 months (n=13), and 81/100 at 12 months (n=9 {6 have not reached 12 months}). Panel assessment is scheduled for March when all participants will have reached study completion. ConclusionsPatient satisfaction with reconstruction is higher for PRADA than most other series. This may be due to short follow up or patients perceiving an advantage from participation in the study. The expert panel assessment will be an important comparison. A randomised controlled trial is planned to further assess this pathway.
Code of conduct/disclaimer available in General Terms & Conditions
{{ help_message }}
{{filter}}